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Illustration article santé mentale - La dépression
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Bien-être

Depression

IRIS Prévention
12 August 2026
Depression affects more than 3 million French people each year: it is not a weakness, it is an illness that can be recognized, treated, and cured.

Illustration article mental health - Depression

What if what I feel right now, this fatigue that doesn't go away, this inexplicable emptiness, this pleasure that has disappeared from the activities I loved, deserved to be taken seriously rather than minimized? Depression is one of the most widespread and underdiagnosed illnesses in France. According to INSERM, it affects more than 3 million people each year in our country. The WHO ranks it among the leading global causes of disability. And yet, it is estimated that one in two people do not consult. This article is here to help me recognize how I feel, without judgment, and to show me that there are real and effective solutions.

1. Depression, much more than a bout of the blues

Depression is not a lack of willpower. Nor is it a simple passing sadness that I could chase away by “shaking myself”. It is a recognized disease, with precise neurological and biochemical bases. The brain of a depressed person works differently: the circuits of reward, motivation and emotions are disrupted. The levels of neurotransmitters, serotonin, dopamine, norepinephrine, are dysregulated.

This biological reality does not exclude psychological and social factors, they constantly interact. But it allows us to understand that we do not “cure” depression by forcing ourselves to think positive. Depression can be treated, like a chronic illness, with appropriate support.

ShapeMain FeaturesTypical duration
Major depressionCharacterized depressive episode, intense symptoms affecting all areasSeveral weeks to months
DysthymiaLess intense but persistent chronic depression, often trivialized because “ it's been like this for a long time"At least 2 years
Seasonal depressionLinked to lack of light in autumn-winter, recurrent at the same period4 to 5 months per year
Depression postpartumOccurs after birth, affects mothers and fathers; often undetectedWeeks to months
Hidden depressionHardly visible emotional symptoms, dominant somatic complaints (pain, fatigue)Variable

2. Symptoms I need to learn to recognize

A diagnosis of depression is based on the presence of at least 5 of the following symptoms for at least two weeks, with a significant impact on daily life. Among them, at least one of the two key symptoms must be present:

  • Depressive mood: deep sadness, inner emptiness, almost permanent feeling of despair. I cry easily, sometimes for no apparent reason.
  • Anhedonia: loss of interest or pleasure in activities that I previously enjoyed, hobbies, social relationships, sexuality, work. This is often the most telling signal.
  • Intense fatigue and loss of energy, even after a full night's sleep.
  • Sleep disorders: insomnia (difficulty falling asleep or waking up early) or on the contrary hypersomnia.
  • Changes in appetite and weight, significant loss or gain without dieting.
  • Excessive feeling of guilt, worthlessness, uselessness.
  • Difficulty concentrating, remembering and making decisions.
  • Recurring thoughts of death or suicide.

In case of suicidal thoughts, I immediately contact 3114, National Suicide Prevention Number, available 24/7, free from any telephone.

3. The different forms of depression

Depression is not a unique reality. Identifying the form that concerns me allows me to adapt the support:

4. Factors that weaken, and those that protect

Depression results from an interaction between biological, psychological and environmental vulnerabilities. Knowing these factors helps me act in prevention:- Risk factors: prolonged chronic stress, personal or family history of depression, trauma, social isolation, difficult life events (bereavement, divorce, job loss), chronic sleep disorders, sedentary lifestyle.

  • Protective factors: regular physical activity (demonstrated as effective as an antidepressant for mild to moderate depression according to several meta-analyses), quality social connections, feeling of usefulness and meaning, quality sleep, access to professional support.

Acting on protective factors does not cure established depression, but can significantly reduce the risk of developing one, and speed up recovery when treatment is underway.

5. What works: treatments and how to get help

Depression can be treated effectively in the vast majority of cases. Healing is possible, and it begins with a first step that I do not have to take alone.

My general practitioner: this is the first contact. It assesses the severity, excludes an organic cause and directs towards the correct follow-up. Don’t wait for it to “go away on its own”.

Psychotherapy: cognitive and behavioral therapy (CBT) is the standard treatment for mild to moderate depression, with a high effectiveness rate according to the HAS. Other approaches (interpersonal therapy, EMDR for post-traumatic depression) may also be indicated.

Antidepressants: indicated in cases of moderate to severe depression, they are prescribed and monitored by a doctor. They require several weeks to take full effect and should never be stopped suddenly without medical advice.

What I can do today: maintain even minimal physical activity (a daily walk), maintain even limited social connections, avoid alcohol which aggravates depression, and not isolate myself further.

💡 tips to remember

    • Depression is not a lack of will: it is a disease that changes the functioning of the brain. Allowing myself to acknowledge it without shame is the first step towards wellness.
    • If I have been experiencing persistent depressed mood or loss of interest for more than two weeks, I make an appointment with my GP. He is the first contact, above all a specialist.
    • Regular physical activity (30 min, 3 times a week) is as effective as an antidepressant for mild to moderate depression according to several scientific meta-analyses. Even a daily walk makes a difference.
    • I maintain my social connections even when I feel like isolating myself: isolation is a major aggravating factor in depression. Forcing a little contact, even minimal, is protective.
    • Depression can be treated effectively in the vast majority of cases. Healing is possible, it starts with asking for help, and I don't have to do this alone.